Earthquakes are gender neutral - they affect everyone in their vicinity - but their impacts are not. Gender inequality exacerbates the impact of disasters, and the impacts of disasters exacerbate gender inequality. The earthquake in Türkiye and Northwest Syria – the largest earthquake to affect the region in 200 years - occurred in areas already affected by mass displacement and population movements for over a decade, as well as long-standing protection issues. One thing is clear, however, where the impacts of the earthquake are gendered, the response must be too. This first Rapid Gender Analysis (RGA) Brief explores existing gender, age and disability data and information to understand pre-existing vulnerabilities and capacities and how best humanitarians can respond to meet people’s different needs.